SC12 Home > SC12 Schedule > SC12 Presentation - Stochastic Simulation Service - Towards an Integrated Development Environment for Modeling and Simulation of Stochastic Biochemical Systems

SCHEDULE: NOV 10-16, 2012

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Stochastic Simulation Service - Towards an Integrated Development Environment for Modeling and Simulation of Stochastic Biochemical Systems

SESSION: Algorithmic Innovations for Large-Scale Computing

EVENT TYPE: Keynote and Invited Talks

TIME: 4:15PM - 5:00PM

SESSION CHAIR: Bernd Mohr

Presenter(s):Linda Petzold

ROOM:Ballroom-EFGH

ABSTRACT:
In recent years it has become increasingly clear that stochasticity plays an important role in many biological processes. Examples include bistable genetic switches, noise enhanced robustness of oscillations, and fluctuation enhanced sensitivity or stochastic focusing". In many cellular systems, local low species populations can create stochastic effects even if total cellular levels are high. Numerous cellular systems, including development, polarization and chemotaxis, rely on spatial stochastic noise for robust performance. In this talk we report on our progress in developing next-generation algorithms and software for modeling and simulation of stochastic biochemical systems, and in building an integrated development environment that will enable researchers to build a such a model and scale it up to increasing levels of complexity.

Chair/Presenter Details:

Bernd Mohr (Chair) - Juelich Supercomputing Center

Linda Petzold - University of California, Santa Barbara

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